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SRS : Spatiallly Resolved Spectroscopy

Standard Visible and Near-Infrared (NIR) Spectroscopy performs one single spectrum measurement per sample. Spatially Resolved Spectroscopy (SRS) performs measurements at different distances from the illumination point. This approach provides chemical information but also physical one such as particle size and shape, cell density, uniformity and even weight. The surface analyzed is also much more important which copes for recommendation of pharmacopeia. Several research centers have demonstrated the superiority of SRS and multipoint imaging techniques over standard NIR one.

Hy-Ternity ® and SAM-Spec ® Probes

INDATECH is currently the only company providing a full SRS/ multipoint solution for industrial applications. The best performance is achieved thanks to two important criteria :

Unique probe design : improved during years and experience, it is protected by several patents (homogeneity measurement, weight , filling).

Fast, robust , reliable multichannel sensor. Rather than using a standard spectrometer, Hy-Ternity® relies on push broom imaging sensor, the same as NIR hyperspectral cameras.

The software can communicate with a controller but also with standard software packages for spectral analysis such as Camo Process pulse ®, The Unscrambler®, Eigenvector PLS_Toolbox® or model exporter. Full certification CFR21 part 11 can be achieved.

Research centers involved in this technology :

Axel One industrial platform (FR)

Faculté de pharmacie de Montpellier (FR)

Dusquesne Univertsity (US)

RCPE / Gratz University (AU)

Articles :

 

Application of spectral derivative data in visible and near-infrared spectroscopy,2010 H. Dehghani, Physics in Medecine and Biology

Use Near-Infrared Spatially Resolved Spectroscopy for Tablet Quality Determination,2015, B. Igne and Al, Pharmaceutics, Drug delivery and Pharmaceuticazl technology of near infrared spectroscopy and multipoint measurements for quality control of pharmaceutical drug products , 2016, M. Boiret and al, Analytical & Bioanalytical Chemistry.

Hy-Ternity® video

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