INDATECH

Webinar on physico-chemical characterization of compaction/granulation products
2023-02-14 16:00 - 17:00 (Europe/Paris) | Webinar
With this Webinar on physico-chemical characterization, you can find out how to use hyperspectral imaging for quick identification of your samples.
This webinar will focus on physico-chemical characterization using NIR spectroscopy in industrial pharmaceutical, chemical or agri-food environments in order to characterize the granulation process. Also, NIR spectroscopy ensures easier continuous handling and better homogeneity of the blend under consideration. The disparity of the physico-chemical properties of the samples and their diversity require the measurement of several samples in a single operation. Which is why NIR hyperspectral imaging is used with Hypereal.
Then, it will be necessary to discover and characterize all the key steps in the compaction and granulation process during the process development phases. That is why this webinar will show how a hyperspectral imaging system can be used for physico-chemical characterization of these intermediate compacted products by indicating the compaction force applied to a powder blend, the proportion of API in the blend or the granule size.
The results are provided as an image, allowing the operator to gain a fuller understanding for optimization of the process and the machine. HypeReal can be used to indirectly assess the chemical composition of the samples, their residual moisture content and other critical quality criteria, without destroying or modifying the sample and without using toxic reagents.
The unique HypeReal inspection system developed by INDATECH is an ideal tool for quick, non-destructive, laboratory-scale analyses of solid dosage forms.
Read the Case Study on physico-chemical characterization of powder blends.

Bioprocessing Summit Europe
2023-03-14 - 2023-03-16 | Intercontinental Barcelona, InterContinental Barcelona- Fira Center, Barcelona, 08004, Espagne
Indatech at the Bioprocessing Summit Europe – March 14-16 in Barcelona, Spain
Indatech‘s team is looking forward to seeing you in Barcelona. We will be there with great demonstrations of Raman and UV VIS.
Bioprocessing Summit Europe will be held from March 14 to 16, 2023 at the Intercontinental Barcelona in Spain. This event brings together over 500 biomanufacturing, analytical and formulation professionals to advance the manufacturing, quality and control of biological and genetic therapies.
Come and see our solutions such as Asuryan and Viserion directly at our booth number 34!

Webinar on the interest of online sugar color measurement (ICUMSA) in the food industry
2023-03-28 16:00 - 17:00 | Webinar
In this webinar on sugar color measurement, you will learn how to measure it online to determine its quality and value.
Most food industries use sugar. Its purity depends on the final quality of the product, especially for beverages. The measurement of the color of sugar (in syrup or solid state) is the main criterion currently recognized. The international laboratory ICUMSA sets the standard for determining the amount of impurities.
Sugar industry is trying to increase the quality of their product to facilitate export and value. Especially true for some countries like Thailand or Brazil.
That is the reason why in-line sugar color measurement is becoming particularly critical to reduce reprocessing costs and gain efficiency. In order to meet this demand, INDATECH has developed an innovative solution capable of working on large ranges. Moreover, its solution meets the needs of both the sugar and the beverage industry.
This webinar is dedicated to sugar color measurement. It will present a collaboration made between NOVASEP and INDATECH. The sensor is directly integrated on filtration units that measure several wavelengths by LED technology.
Our specialist will present how to calibrate a sensor from the laboratory. After the calibration, he will explain the placement directly on the production line. An essential step for realizing a real time measurement in the process allowing an interaction and a piloting. To know the composition of your liquids with accuracy, the SPOT4Line solution uses the LED light beam that penetrates the liquid to bring out its “optical fingerprint” and validate in real time several parameters.
INDATECH is a recognized player in spectroscopy and holder of numerous patents. It has designed SPOT4Line, the first multi-angle LED spectrometer dedicated to the analysis of all industrial liquids. Based on spectral scattering of light, SPOT4Line is completed by the patented SAM-SPEC Spatially Resolved Spectroscopy (SRS) technology to assign an optical signature to the liquid measured.
Discover all our application notes on the SPOT4Line.

France Bioproduction Congress
2023-04-05 - 2023-04-06 | Palais des Congrès de Tours, 26. Bd Heurteloup, Tours, 37000, France
Indatech will be at the France Bioproduction Congress –April 5th to 6th in Tours, France
The France Bioproduction Congress will be held from April 5th to 6th, 2023 at the Palais des Congrès in Tours. This event brings together more than 450 players from the pharma and biopharma sectors. These decision-makers and actors in French pharmaceutical bioproduction will be meeting for two days of conferences, round-table discussions and practical workshops.

Indatech’s teams are looking forward to meeting you at this event in Tours. We will be there with some fine demonstrations of UV VIS spectroscopy.

Come and discover our solutions such as Asuryan directly at Booth 12!

Indatech is a member of Polepharma and is thus participating in the development of the bioproduction industry. More than 400 industrial companies have also chosen to join Polepharma which groups all the players in the sector: research laboratories, production sites, third-party manufacturers, suppliers and training centers.

Swiss Biotech Day
2023-04-24 - 2023-04-25 | Congress Center Basel, Messeplatz 21, Basel, 4058, Suisse
Indatech present at the Event Swiss Biotech Day –April 24th to 25th in Bâle, Switzerland
The Swiss Biotech Day event will be held from April 24th to 25th, 2023, at the Basel Congress Center in Switzerland. This event brings together more than 1,000 biotechnology, analysis and formulation experts to improve manufacturing, quality and control of biological and genetic therapies.
Indatech’s teams are looking forward to meeting you at this event in Bâle. We will be there with some fine demonstrations of UV VIS spectroscopy
Come and discover our solutions such as Asuryan directly at Booth 13!

Webinar on determination of protein aggregation by inline UV/Vis spectroscopy
2023-05-16 16:00 - 17:00 | Webinar
At this webinar, find out about inline measurement of protein aggregation during biopharmaceutical production.

Protein aggregation
Protein aggregation is one of the most frequent causes of protein instability. Considered a critical quality attribute, this is an essential indicator in drug manufacture, whether upstream or downstream.
The development and production of pharmaceutical products such as monoclonal antibodies may be affected by protein aggregation. This phenomenon occurs in various production, storage and sample handling conditions. As well, this occurs in a large range of protein concentrations and formulations. The presence of aggregated forms of proteins is potentially problematic for these therapeutic products. It brings with it a risk of immunogenic and pharmacokinetic problems.
Consequently, it is essential to fully characterize, quantify and check the level of aggregates, their nature and their distribution. In the context of an effective analytical inspection strategy for biological and biopharmaceutical products, these checks need to be performed regularly.
Characterization and inspection
Although most aggregates form during the upstream operations, they may also occur during the downstream processing, for example when unsuitable conditions have been selected.
Successful bioproduction therefore requires thorough knowledge of the processes and a rigorous definition of their parameters.
This is why, during this webinar, we will be explaining how our Asuryan UV-Vis spectrometer can be used to acquire knowledge concerning the processes, whether during the R&D phases to reduce the time-to-market, or directly inline for early detection of protein aggregation to avoid reduced product yields. Proteins, which are highly reactive molecules, are present in small quantities. They require a spectroscopy method suitable for such low concentrations. Thanks to its high sensitivity, UV spectroscopy is ideal for this type of measurement.
Furthermore, the adaptability of the Asuryan’s UV spectroscopic measuring system enables various different probes to be used. These cover the wide ranges of protein concentrations encountered in the different industries and during the various steps for their production.
An acknowledged player in spectroscopy and the owner of a large number of patents, INDATECH has designed Asuryan, an inline measuring and inspection solution ideal for therapeutic production:

Measurement sensitivity and accuracy at low concentrations,
Repeatability over time thanks to an internal reference measurement,
Simultaneous measurements at several points with different protein concentrations.

See all our case studies involving Asuryan.

IFPAC 2023
2023-06-04 - 2023-06-07 | Bethesda North Marriott, North Bethesda, Maryland, Washington, D.C., USA
Indatech present at IFPAC 2023 –June 4th to 7th at North Bethesda in the USA
IFPAC 2023 will be held from June 4th to 7th at the Marriot Hotel in North Bethesda, Maryland. This event brings together experienced professionals and future leaders in Process Analytical Technology (PAT). Every year, ideas are discussed for the future well-being of the industry.
Indatech’s teams are looking forward to meeting you at this event in the United States. We will be there with some fine demonstrations of UV VIS spectroscopy and hyperspectral imaging.
Come and discover our solutions such as Asuryan and HypeReal directly at our booth!
Since 1987, the conferences at IFPAC have been a great success. This is why they have led to the creation of a series of international meetings bringing together the regulation organizations, manufacturers, researchers and industrial users. Register today to see all the equipment and services on show!
That way, you can keep informed about the latest trends and concrete applications in sectors such as Quality By Design, process analytical technology, emerging technologies, quality measurements, continuous manufacturing and process control applications for the pharmaceutical, biotechnological, generic, chemical, petrochemical and agri-food industries, to quote just a few.

BioProcess International 2023
2023-09-18 - 2023-09-21 | Boston Convention and Exhibition Center, 415 Summer Street, Boston, Massachusetts, MA 02210
Indatech will be at BioProcess International 2023 –September 18th to 21st in Boston, USA
BioProcess International 2023 will be held from September 18th to 21st at the Boston Convention and Exhibition Center in the USA. This event brings together more than 2,700 professionals from more than 30 countries. The event focuses on scientific research and innovative technologies concerning bioprocesses.
Indatech’s teams are looking forward to meeting you at this event in the United States. We will be there with some fine demonstrations of UV VIS and Raman spectroscopy.
Come and learn how to speed up promising biological, cellular and genetic therapies. Take advantage of this opportunity to discover our solutions such as Asuryan and Viserion directly at Booth 761!

Webinar on the application of near-infrared hyperspectral imaging to solid dosage forms, from the laboratory through to production
2023-10-03 16:00 - 17:00 | Webinar
Come and debate with our guest, Jan-Sebastiaan Uyttersprot, Principal Scientist for product design and performance at UCB Pharma.

In this webinar, Jan-Sebastiaan Uyttersprot, Principal Scientist at UCB Pharmaceuticals (Union Chimique Belge), will explain how he approaches solving problems linked to the development of a PAT (Process Analytical Technology) method.

Summary of the webinar presented by Jan-Sebastiaan Uyttersprot

Even if you perform all the correct steps to validate a PAT method, it does not guarantee that the method will fulfill all the required criteria for success.

Analysis and troubleshooting of the underlying causes require an even more extensive PAT toolbox, as well as knowledge of data science. During the presentation, we will discuss the lessons learned and how to avoid similar difficulties in future projects.

Summary of the webinar presented by Davinia Brouckaert

Process Analytical Technology (PAT) can really change things if it is applied correctly. However, to take full advantage of PAT’s inherent benefits, you need to avoid certain difficulties during development of the method. In this webinar, Jan-Sebastiaan Uyttersprot of UCB Pharmaceuticals will explain how he approaches solving problems linked to the development of a PAT (Process Analytical Technology) method. In his quest for a PAT tool based on spectroscopy for real-time inspection of solid dosage forms, he looked into various technologies, from the laboratory through to production, seeking significant, information-rich data. During the presentation, he will discuss his own experience with Raman imaging, Raman transmission, NIR hyperspectral imaging and in-line spatially-resolved spectroscopy. He will also share the results of an industrial case study and compare the strengths and weaknesses of the technologies assessed.

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INDATECH products presented

HypeReal: bench-top near-infrared hyperspectral imaging solution
SAM-Spec Solids: spatially-resolved near-infrared spectroscopy probe integrated in the CU-120 machine from Pharma Technology

See all our Case Studies on HypeReal and SAM-Spec.

AAPS 2023 PharmaSci 360
2023-10-22 - 2023-10-25 | Orange County Convention Center, 9800 International Dr, Orlando, FL 32819, USA
Indatech present at AAPS 2023 PharmaSci 360 – October 22nd to 25th in Orlando, USA
AAPS 2023 PharmaSci 360 will be held from October 22nd to 25th at the Orange Convention Center in the USA. This is a worldwide event bringing together scientists working in the pharmaceutical sector.
Indatech’s teams are looking forward to meeting you at this event in the United States. We will be there with some fine demonstrations of UV VIS and Raman spectroscopy.
Come and discover our solutions such as Asuryan and Viserion directly at Booth 2115 !

Webinar : Real-time crystallization monitoring using Raman spectroscopy and kinetic models
2023-11-21 16:00 - 17:00 | Webinar
Summary of the webinar
The purity of an active pharmaceutical ingredient (API) is crucial in the pharmaceutical industry. Impurities can alter the effectiveness of the drug and lead to undesirable effects. This is why pharmaceutical regulations impose strict purity standards for APIs, requiring rigorous manufacturing processes and stringent quality controls. Process analytical technology (PAT) serves as a valuable tool for real-time monitoring of product quality attributes, enhancing the overall quality control process.
In this webinar, we will present a collaborative study between Indatech and Rowan University in the USA. The study focused on the utilization of Raman spectroscopy as a PAT tool for the in-line monitoring of the crystallization process of acetaminophen, a commonly used small-molecule API, and curcumin, a simulated impurity with low solubility and co-precipitation tendencies. The Raman results were used to calibrate a population balance model, enabling the prediction of the product’s purity evolution throughout the manufacturing process.
SPEAKER
Mitchell Paolello is a PhD student at Rowan University whose primary research interest is the diagnosis of impurity incorporation mechanisms in pharmaceutical crystallization processes. Most of his work is centered around investigating how impurities incorporate and are retained thermodynamically and kinetically, especially in the context of crystalline solid solutions. He has coauthored a published paper and submitted two papers on case studies of impurity retention mechanisms in both academic and industrial processes. His overall goal is to help improve understanding of the mechanisms in which impurity incorporation and retention occur in pharmaceutical crystallization systems with the purpose of enabling more robust process design. Before coming to Rowan, Mitchell earned his BS in Chemical Engineering at Drexel University and is also currently a co-op in the Solid State and API Engineering division at Boehringer Ingelheim.

IFPAC 2024
2024-03-03 - 2024-03-06 | Bethesda North Marriott, North Bethesda, Maryland, Washington, D.C., USA
Indatech present at the IFPAC 2024 show – from March 3rd to 6th, 2024, in Bethesda, Maryland, USA Dedicated to the latest developments in quality by design, emergent technologies and quality measurements, IFPAC is the essential meeting place for all the pharmaceutical, biotechnological and chemical industries.
At this event, experts and scientists come together to discuss the technologies to improve industrial processes.
As an actor in Industry 4.0, Indatech offers a dynamic approach to production by providing accurate real-time measuring solutions.

Come to our Booths nos. 407 & 409 and discover in person our broad product range: Asuryan, Raman and HypeReal.
Our latest innovations include a new Raman probe capable of cutting sensitivity to external light by 90% and our new flow-cell probe with three adjustable optical paths which is ideal for downstream processes.

Webinar : Fast and non-destructive quality control of lyophilized vials: in-line crack detection and residual moisture prediction
2024-03-12 16:00 - 17:00 | Webinar
Summary of the webinar
The pharmaceutical industry, due to its direct impact on public health, places crucial importance on the quality control of its products. This is particularly significant in the case of lyophilized vaccines, where aspects such as residual moisture content and the physical appearance of lyocakes are of strategic importance, directly impacting the stability and efficacy of the vaccine. The stringent quality control becomes imperative to ensure patient safety and meet the strict regulatory standards governing this delicate industry.

In this webinar, we will present a study conducted in collaboration with a client, whose anonymity, as well as that of the examined product, will be preserved for confidentiality reasons. The study focused on quantifying the residual moisture content in lyophilized vaccine samples and analyzing appearance defects such as cracks using spatially resolved near-infrared spectroscopy (NIR-SRS) and hyperspectral imaging. Sample were measured in the laboratory to demonstrate the capabilities of the SAM-Spec system at-line, with the future intention of real-time inspection of manufactured products directly in-line. Presented products Indatech

HypeReal: benchtop pushbroom imaging system for at-line NIR hyperspectral imaging
SAM-Spec: spatially resolved NIR spectroscopy for high throughput in-line measurements

France Bioproduction Congress
2024-04-03 - 2024-04-04 | Palais des congrès Paris Saclay à Massy, 19 Pl. du Grand Ouest, Massy, 91300, France
Indatech will be at the France Bioproduction Congress –April 3rd to 4th in Paris, France

The France Bioproduction Congress will be held from April 3rd to 4th, 2024 at the Palais des Congrès in Paris. This event brings together more than 450 players from the pharma and biopharma sectors. These decision-makers and actors in French pharmaceutical bioproduction will be meeting for two days of conferences, round-table discussions and practical workshops.

Indatech’s teams are looking forward to meeting you at this event in Paris. We will be there with some fine demonstrations of UV VIS spectroscopy.

Come and discover our solutions such as Asuryan directly at Booth 20!

Indatech is a member of Polepharma and is thus participating in the development of the bioproduction industry. More than 400 industrial companies have also chosen to join Polepharma which groups all the players in the sector: research laboratories, production sites, third-party manufacturers, suppliers and training centers.

The 25th HélioSpir Worskshop: June 11th & 12th, 2024, in Montpellier
2024-06-11 - 2024-06-12 | Agropolis International Montpellier, 1000 Av. Agropolis, Montpellier, 34000
Indatech present at the 25th HélioSPIR Workshop in Montpellier

The 25th HélioSPIR Worskop will be held on June 11th and 12th, 2024, on the Agropolis International site in Montpellier!
Indatech’s team is delighted to be attending to celebrate HélioSPIR’s 20th anniversary on June 11th and 12th, 2024, on the Agropolis International site in Montpellier.
Like every year, the scientific workshop will offer privileged discussions around various topics linked to near-infrared spectroscopy and a chance to learn about the latest work in the community. You will also be able to check out the spectroscopy and hyperspectral imaging equipment from the main manufacturers in the sector, including Indatech.
Lastly, these workshops will be an excellent opportunity to discuss the advances and methods in spectroscopic data analysis.
Don’t miss the conference by Ilys Bichari, PAT Application Engineer at INDATECH, scheduled for 5 PM on Wednesday June 12th, 2024, on “Assessment of enzymatic reactivity on biomass samples by near-infrared imaging.”.

Founded in 2004, the HélioSPIR Association organizes one or more “Scientific Workshops” every year around topics related to Near-Infrared Spectroscopy (NIR) and chemometrics or Machine Learning. The purpose of the association is to federate scientists and users in the French-speaking spectroscopy community within a network to promote the use of near-infrared spectroscopy.

A3P Biotherapy Process Day
2024-11-21 | Lyon – Mercure Château Perrache, Esplanade De La Gare, 12 Cr de Verdun Rambaud, Lyon, 69002, France
A3P Biotherapy Process Day, Indatech Booth 13 – November 21st in Lyon (France)

We are delighted to announce that Indatech will be taking part in the event dedicated to Biotherapy Processes organized by A3P in Lyon on November 21st, 2024. This event aims to bring together the main actors in the field, including start-ups, industrial companies , CDMOs, suppliers and service providers.
Organized following the 2023 event, this day will provide an opportunity to present the work by the GIC and share relevant feedback between the CDMOs and start-ups. Indatech will be there to show you our innovative inspection and analysis solutions for optimizing bioproduction processes.
We invite you to join us in order to explore together the new trends and technologies shaping the future of biotherapies.
We will be present as exhibitors at Booth 15: come and check out our solutions!

Webinar : Raman spectroscopy and Machine Learning as a PAT tool for mAbs bioprocessing
2024-12-10 16:00 - 17:00 | Webinar
Summary of the webinar
In-line Raman spectroscopy, coupled with machine learning tools, enables non-destructive analysis of bioprocesses, such as the production of monoclonal antibodies (mAbs) in cell cultures. Through real-time monitoring of critical process parameters (CPPs) and critical quality attributes (CQAs), such as nutrient and metabolite concentration, viable cell density and mAb concentration, batch reproducibility and yield may be significantly improved.
The developments and results presented in this webinar were carried out in the context of CLIMBIN. CLIMBIN is a collaborative project that aims to provide the bioproduction sector with an innovative solution in process analytical technology (PAT) by molecular optical spectrometry, ready to use and adapted to CHO-type suspension cultures in various types of bioreactors. This real-time monitoring of critical process and quality parameters offers disruptive advantages in terms of control, industrial performance and CSR.
We will present key hardware developments, including innovative probe tips for increased Raman sensitivity, as well as reduced interference from ambient light and media turbidity. An industrial case study on fed batch cell cultures in 10-liter bioreactors will be presented, demonstrating the machine learning model development approach on the path to fully automated process control. Presented products Indatech

Viserion Raman spectrometer
VSP-IM Raman immersion probes

IFPAC 2025
2025-03-02 - 2025-03-05 | Bethesda North Marriott, North Bethesda, Maryland, Washington, D.C., USA
Indatech present at the IFPAC 2025 show – from March 2nd to 5th, 2024, in Bethesda, Maryland, USA

Dedicated to the latest developments in quality by design, emergent technologies and quality measurements, IFPAC is the essential meeting place for all the pharmaceutical, biotechnological and chemical industries.
At this event, experts and scientists come together to discuss the technologies to improve industrial processes.
As an actor in Industry 4.0, Indatech offers a dynamic approach to production by providing accurate real-time measuring solutions.

Come to our Booths nos. 407 & 409 and discover in person our broad product range: Asuryan, Raman and HypeReal.
Our latest innovations include a new Raman probe capable of cutting sensitivity to external light by 90% and our new flow-cell probe with three adjustable optical paths which is ideal for downstream processes.

France Bioproduction 2025
2025-03-19 - 2025-03-20 | Palais des Congrès de Tours, 26. Bd Heurteloup, Tours, 37000, France
Indatech at France Bioproduction: innovative solutions for the biopharmaceutical industry Indatech will be exhibiting at France Bioproduction, the leading event dedicated to the development of the biomanufacturing sector in France. We will be presenting our innovative spectroscopy solutions, designed to optimize manufacturing processes and guarantee real-time quality control in the biopharmaceutical industry.
📍 Join us at France Bioproduction to talk to our experts and discover our technologies for tomorrow’s biomanufacturing!
