{"id":14541,"date":"2024-10-22T13:57:16","date_gmt":"2024-10-22T11:57:16","guid":{"rendered":"https:\/\/indatech.eu\/evenement\/webinar-la-spectroscopie-raman-et-le-machine-learning-comme-outil-pat-pour-la-production-des-biotraitements-mabs\/"},"modified":"2024-10-22T14:14:27","modified_gmt":"2024-10-22T12:14:27","slug":"webinar-raman-spectroscopy-and-machine-learning-as-a-pat-tool-for-mabs-bioprocessing","status":"publish","type":"tribe_events","link":"https:\/\/indatech.eu\/en\/evenement\/webinar-raman-spectroscopy-and-machine-learning-as-a-pat-tool-for-mabs-bioprocessing\/","title":{"rendered":"Webinar : Raman spectroscopy and Machine Learning  as a PAT tool for mAbs bioprocessing"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css=&#8221;.vc_custom_1647527410858{margin-right: 0px !important;margin-left: 0px !important;padding-right: 0px !important;padding-left: 0px !important;}&#8221;][vc_column][vc_column_text font_size=&#8221;24&#8243; text_resize=&#8221;yes&#8221; text_minimum=&#8221;26&#8243; font_color=&#8221;#73797d&#8221;][\/vc_column_text][cesis_line_divider pos=&#8221;cesis_line_d_left&#8221; height=&#8221;8&#8243; width=&#8221;100&#8243; color=&#8221;#ffdf0e&#8221; css_animation=&#8221;fadeInLeft&#8221; margin_top=&#8221;-8&#8243;][vc_empty_space][vc_column_text css=&#8221;&#8221;]<strong>Summary of the webinar<\/strong><\/p>\n<p>In-line Raman spectroscopy, coupled with machine learning tools, enables non-destructive analysis of bioprocesses, such as the production of monoclonal antibodies (mAbs) in cell cultures. Through real-time monitoring of critical process parameters (CPPs) and critical quality attributes (CQAs), such as nutrient and metabolite concentration, viable cell density and mAb concentration, batch reproducibility and yield may be significantly improved.<\/p>\n<p>The developments and results presented in this webinar were carried out in the context of CLIMBIN. CLIMBIN is a collaborative project that aims to provide the bioproduction sector with an innovative solution in process analytical technology (PAT) by molecular optical spectrometry, ready to use and adapted to CHO-type suspension cultures in various types of bioreactors. This real-time monitoring of critical process and quality parameters offers disruptive advantages in terms of control, industrial performance and CSR.<\/p>\n<p>We will present key hardware developments, including innovative probe tips for increased Raman sensitivity, as well as reduced interference from ambient light and media turbidity. An industrial case study on fed batch cell cultures in 10-liter bioreactors will be presented, demonstrating the machine learning model development approach on the path to fully automated process control.[\/vc_column_text][vc_empty_space height=&#8221;20px&#8221;][cesis_button button_text=&#8221;FREE REGISTRATION&#8221; link=&#8221;https:\/\/webinar-chauvin-arnoux.webex.com\/weblink\/register\/reac0dab0ef9d10e96d1d7cca2daea9dd&#8221; target=&#8221;_blank&#8221; button_pos=&#8221;center&#8221; button_radius=&#8221;8&#8243; hover=&#8221;trim&#8221; button_text_color=&#8221;#000000&#8243; button_bg_color=&#8221;#eeee22&#8243; button_border_color=&#8221;#0a0a0a&#8221; h_button_text_color=&#8221;#0a0a0a&#8221; h_button_bg_color=&#8221;#ffffff&#8221; h_button_border_color=&#8221;#0a0a0a&#8221;][vc_empty_space height=&#8221;60px&#8221;][vc_column_text css=&#8221;&#8221;]<strong>Presented products Indatech<\/strong><\/p>\n<ul>\n<li>Viserion Raman spectrometer<\/li>\n<li>VSP-IM Raman immersion probes<\/li>\n<\/ul>\n<p>[\/vc_column_text][cesis_button button_text=&#8221;MORE INFORMATIONS&#8221; link=&#8221;https:\/\/indatech.eu\/en\/viserion\/&#8221; target=&#8221;_blank&#8221; button_radius=&#8221;8&#8243; hover=&#8221;trim&#8221; button_text_color=&#8221;#ffffff&#8221; button_bg_color=&#8221;#0a0a0a&#8221; button_border_color=&#8221;#0a0a0a&#8221; h_button_text_color=&#8221;#0a0a0a&#8221; h_button_bg_color=&#8221;#ffdf0e&#8221; h_button_border_color=&#8221;#0a0a0a&#8221;][vc_empty_space height=&#8221;60px&#8221;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Assistez \u00e0 notre webinar le mardi 10 d\u00e9cembre \u00e0 16h !<\/p>\n","protected":false},"author":8,"featured_media":14537,"template":"","meta":{"_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":""},"tags":[225],"tribe_events_cat":[187],"class_list":["post-14541","tribe_events","type-tribe_events","status-publish","has-post-thumbnail","hentry","tag-webinar-en","tribe_events_cat-webinar-en","cat_webinar-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Webinar : Raman spectroscopy and Machine Learning as a PAT tool for 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